49ers who will have major impact in Week 3 vs. Steelers

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They are going to have a great shot of doing so next Sunday when they take on the hobbled Pittsburgh Steelers at Levi's Stadium.

So far in the young season, the Steelers' Ben Roethlisberger is out for the year, while the Colts saw Andrew Luck retire.

But the move from Pittsburgh's perspective is a surprise, seeing as the Steelers also are winless and now without starting quarterback Ben Roethlisberger, who will miss the rest of the season after suffering an elbow injury.

At this point, we do not know what Mason Rudolph can do for the Pittsburgh Steelers at the quarterback position.

Head coach Mike Tomlin said Roethlisberger underwent an MRI exam on Sunday night and team doctors determined Roethlisberger requires surgery. There was no immediate timetable on his possible return. He holds the club record in just about every major statistical passing category, including yards (56,545), touchdowns (363), attempts (7,230) and completions (4,651).

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Roethlisberger was 8-for-15 for 75 yards before leaving the game.

He was drafted by the Steelers with the 76th pick in the 2018 draft.

None of Joe Haden (shoulder), James Conner (knee) Roosevelt Nix (knee), Anthony Chickillo (plantar fasciitis) or Vince Williams (hamstring) practiced on Wednesday as the Steelers began practicing for the San Francisco 49ers.

"You've got to be prepared for those situations, whenever your number is called, and I thought I was ready", Rudolph, a third-round pick in the 2018 National Football League draft, said to reporters after Sunday's game. "If (Roethlisberger is out a while), I'm ready to roll".

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